<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI NA
2 3TC+AZT+IDV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI   T12S, K14R, I15V, L19I, M36I, R41K, L63PS, H69K, T74S, L89M, I93L  
>1183| codons 4-99
TLWQRPLVSIRVGGQIKEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYDQIS
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39E, V60I, A98S, D121H, K122E, I135KR, I142IV, K166R, K173A, Q174R, D177E, T200A, I202V, Q207E, R211K, V245Q  
>1183| codons 38-247
CEEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSRNNETPGVRYQYNVLPQGWKGSP
AIFQSSMTRILEPFRARNPEIVIYQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014