<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI NA
2 D4T+DDI+LPV 148

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I47A   T12S, I13IV, I15V, L19K, K20I, M36I, Q61E, L63T, H69K, T74S, L89I, I93L  
>311| codons 4-99
TLWQRPLVSVKVGGQKIEALLDTGADDTVLEEINLPGRWKPKLAGGIGGFIKVRQYDEIT
IEICGKKAIGSVLVGPTPVNIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, D67N, L210W, T215Y       T39EK, K49R, E53D, D121H, K122E, A158S, T165I, E169D, K173A, Q174K, D177E, G196E, T200A, Q207E, F214FL, V245Q  
>311| codons 38-247
CKEMEKEGKISRIGPDNPYNTPVFAIKRKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
SIFQSSMIKILDPFRAKNPEIVIYQYMDDLYVGSDLEIEQHRAKIEELREHLWRWGLYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014