Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTI | NA |
| 2 | D4T+DDI+LPV | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T74TP | T12S, I15V, L19IT, K20KI, E35ED, M36I, Q61E, L63T, H69K, L89IM, I93L |
| >311| codons 4-99 TLWQRPLVSIKVGGQTIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYDEIT IEICGKKAIGPVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, L210W, T215Y | K101KE | T39EK, K49R, E53D, D121DH, K122E, D123DGNS, A158S, T165I, E169D, K173A, Q174K, D177E, I180IL, G196E, T200A, Q207E, V245Q |
| >311| codons 38-247 CKEMEKEGKISRIGPDNPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLHESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP SIFQSSMIKILDPFRAKNPEIVLYQYMDDLYVGSDLEIEQHRAKIEELREHLWRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. | PLoS ONE, 2014 |