<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+LPV+TDF 65

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L10F I13V, G16Q, K20I, M36I, P39L, I62V, L63P, H69K, L89M  
>554| codons 4-99
TLWQRPFVTVKIQGQLIEALLDTGADDTVLEEINLLGRWKPKIIGGIGGFVKVRQYDQVP
IEICGKKAIGTVLVGPTPANIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184I       K43N, W88C, K122E, E138A, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q  
>554| codons 38-247
CTEMENEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP
AIFQASMTKILEPFRTKNPEIVIYQYIDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014