<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+LPV 52
2 3TC+D4T+DDI+LPV 67

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48M, I54V, V82A L24I, L33LF, F53FL L10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, V77VI  
>27| codons 4-99
TLWQRPIVTIKIGGQLREALIDTGADDTVFEDINLPGKWKPKMIMGIGGLVKVKQYEDVP
IEICGHKAIGTVLIGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, T215Y K219E     V60VI, S105A, K122E, I135IV, D177E, I178M, L228H F214FY
>27| codons 38-247
CTELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKAVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEMVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGYYTP
DEKHQKEPPFHWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014