<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NFV|RTI NA
2 3TC+D4T+LPV 52
3 D4T+DDI+LPV 82

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A L10F, L33F I13V, I15V, G16E, K20R, M36I, R41K, L63Q, H69K, L89I, I93L  
>849| codons 4-99
TLWQRPFVTVKVEGQLREALLDTGADDTVFEEINLPGKWKPKIIGGIGGFVKVRQYDQIQ
IEICGKKAIGTVVVGPTPANIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       T39EK, K122E, D123NS, K173T, Q174K, D177E, I178M, T200A, E203K, Q207E, V245T  
>849| codons 38-247
CKEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRTKNPEMVIYQYVDDLYVGSDLEIGQHRAKIKELREHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPITLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014