<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|RTV NA
2 D4T+DDI+LPV 52
3 3TC+AZT+LPV 215
4 3TC+D4T+LPV+RAL 47

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A, L90M   L10V, I15V, L19V, K20R, M36I, N37D, R41K, K55R, R57K, Q61E, L63P, H69K, A71V, T74TS, L89M, I93L  
>52| codons 4-99
TLWQRPVVTIKVGGQVREALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVRVKQYDEIP
IEICGKKVIGSVVVGPTPANIIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, K70R, Y115F, Q151M V75I, F77L, F116Y, K219Q V106M, G190A   T39D, S68G, T69K, V90I, A98S, K102Q, V118I, K122E, D123S, I135T, S162A, R172K, K173T, Q174K, D177E, T200A, I202V, F214L, L228H, V245Q  
>52| codons 38-247
CDEMEKEGKISKIGPENPYNTPVFAIKRKDGKRWRKLIDLRELNKRTQDFWEIQLGIPHP
SGLKQKKSMTVLDVGDAFYSIPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP
AIFQASMTKILEPFKTKNPEIVIYQYMDDLYVASDLEIGQHRAKVEELRQHLLRWGLTTP
DQKHQKEPPFHWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014