<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|RTV NA
2 D4T+DDI+LPV 52
3 3TC+AZT+LPV 142

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A, L90M L10FV I15V, L19V, K20R, M36I, N37D, R41K, Q61E, I62IV, L63P, H69K, A71V, I72IT, L89M, I93L  
>52| codons 4-99
TLWQRPVVTIKVGGQVREALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVKVRQYDEVP
IEICGKKVTGTVVVGPTPANIIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, K70R, Y115YF, Q151M V75I, F77L, F116Y, K219Q V106M, G190A   T39D, S68G, A98S, K102Q, V118I, K122E, D123S, I135T, S162A, K173T, Q174K, D177E, T200A, I202V, F214L, L228H, V245Q T69HKNQ
>52| codons 38-247
CDEMEKEGKISKIGPENPYNTPVFAIKRKDGQRWRKLIDLRELNKRTQDFWEVQLGIPHP
SGLKQKKSMTVLDVGDAFYSIPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP
AIFQASMTKILEPFRTKNPEIVIYQYMDDLYVASDLEIGQHRAKVEELRQHLLRWGLTTP
DQKHQKEPPFHWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014