<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|RTV NA
2 D4T+DDI+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54IV, L76V, V82A, L90M   L10V, I15V, L19V, K20R, M36I, N37D, R41K, Q61E, L63PT, H69K, I72IT, L89M, I93L  
>52| codons 4-99
TLWQRPVVTIKVGGQVREALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVKVRQYDEIT
IEICGKKATGTVVVGPTPANIIGRNMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, L74LV K219Q K103KN   T39D, T69TN, A98S, K102Q, V118VI, K122E, D123S, I135T, S162A, K173T, Q174K, D177E, T200A, F214L, L228H, V245Q  
>52| codons 38-247
CDEMEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKVVDFRELNKRTQDFWEVQLGIPHP
SGLKQNKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQASMTKILEPFRTKNPEIVIYQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGLTTP
DQKHQKEPPFHWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014