<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|SQV NA
2 3TC+DDI+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48A, I54V, V82A L10F, L24I, Q58E K20R, M36I, R41K, L63P, H69K, A71V, I72V, N83S, L89I, I93L  
>488| codons 4-99
TLWQRPFVTIKIGGQLREALIDTGADDTVLEEINLPGKWKPKMIAGIGGFVKVREYDQIP
IEICGKKVVGTVLVGPTPASIIGRNILTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, M184V, T215F K219E     T39K, K43E, T69N, K122E, D123S, F124FL, I142V, S162Y, K173A, Q174K, D177E, T200A, Q207E, R211K, L228H, V245Q D113DN
>488| codons 38-247
CKELEEEGKISKIGPENPYNTPVFAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGNAYFSVPLDESLRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFFTP
DEKHQKEPPFHWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014