<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|SQV NA
2 3TC+AZT+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV, V82A, L90M L10F, N88ND Q7X, I15V, L19I, K20KR, M36I, R41K, Q61H, I62V, L63P, H69K, A71V, L89IM, I93L R8~
>389| codons 4-99
TLWX~PFVTIKVGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFVKVRQYDHVP
IEICGKKVIGTVLVGPTPANIIGRDMMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y   Y188L   T39E, S48T, L109I, K122E, D123S, A158S, K173A, D177E, G196K, T200A, Q207E, R211K, D237DN, V245Q R78RG
>389| codons 38-247
CEELEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFGELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVIDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRAQNPEIVIYQYVDDLLVGSDLEIKQHRAKIEELREHLWKWGFYTP
DKKHQKEPPFLWMGYELHPNKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014