<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NFV|RTI NA
2 D4T+DDI+LPV 52
3 DDI+EFV+LPV 221

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T215Y   L100LI, K103N, V106VM   T39DE, V90VI, A98S, K122E, D123S, T139TI, A158S, K173A, Q174K, D177E, G196E, T200A, Q207E, V245Q  
>217| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHP
SGIKKNKSMTVLDVGDAYFSVPLDESFRKYTAFTIPSINNEIPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRAKNPEIVIYQYMDDLYVGSDLEIEQHRAKIEELREHLLRWGFYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, V82A, L90M L33F L10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, K55R, L63E, G68GE, H69Q, A71AV, L89I, I93L  
>217| codons 4-99
TLWQRPIVTVRVGGQLREALLDTGADDTVFEDIELPGKWKPKIIGGVGGFVRVRQYDQIE
IEICEQKVIGTVLVGPTPANIIGRNIMTQLGCTLNF

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014