<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI NA
2 D4T+DDI+LPV 52
3 3TC+AZT+LPV 98

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I47IV   W6L, I15V, M36I, P39PS, R41K, H69K, L89M, I93L  
>83| codons 4-99
TLLQRPLVTIKVGGQLKEALLDTGADDTVLEEINLSGKWKPKMVGGIGGFIKVRQYDQIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103NT, V106VM   T39E, A98S, K102R, K122E, D123G, A158S, K173A, T200A, Q207D, R211K, V245Q G231GE
>83| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLKRTKSMTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRAQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTP
DKKHQKEPPFLWMEYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014