<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NFV|RTI NA
2 3TC+AZT+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82F, L90M   L10I, I13V, I15V, L19T, K20T, E35N, M36I, R41K, K45R, H69K, A71T, T74S, V77I, L89I, I93L C95Y
>183| codons 4-99
TLWQRPIVTVKVGGQTTEALLDTGADDTVLENINLPGKWKPRIIGGIGGFVKVRQYDQIL
IEICGKKTIGSVLIGPTPFNIIGRNIMTQLGYTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y       T39D, S48T, S68G, K122E, D123S, I135T, E138A, A158S, S162C, V179I, T200A, Q207A, R211K, V245Q  
>183| codons 38-247
CDEMEKEGKITKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSP
SIFQCSMTKILEPFRKQNPDIIIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014