<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+DDI+LPV 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y V75M, K219R     E44D, V60I, V118I, K122E, S134SG, Q174K, N175Y, G196E, T200R, Q207E, R211A, D218E  
>33| codons 38-247
CTELEKDGKISKIGPENPYNTPIFAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPGINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKKYPDIVIYQYVDDLYVGSDLEIEQHRRKIEELREHLWAWGFYTP
ERKHQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54IV, L76V, V82A, I84IV, L90LM L10F, Q58E W6WR, I15V, K20R, E34EK, M36I, N37ND, L63LP, H69R, L89LM L24L*, D60EV
>33| codons 5-99
LRQRPFVTIKVGGQLREAL*DTGADDTVLKEIDLPGRWKPKIIGGIGGFVKVREYVQIPI
EICGRKAIGTVVVGPTPANVIGRNMMTQIGCTLNF

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014