<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NFV|RTI NA
2 AZT+LPV+TDF 52
3 DDI+FTC+LPV+TDF 125

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, L76V, V82A L10F T12S, I15V, L19I, K20R, M36I, N37ND, R41K, K55R, R57RK, I62V, L63P, H69K, A71V, I93L  
>946| codons 4-99
TLWQRPFVSIKVGGQIREALLDTGADDTVLEEIDLPGKWKPKIIGGIGGFVRVKQYDQVP
IEICGKKVIGTVVVGPTPANIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R V75VL, T215TI, K219Q K103N P225H, K238T T39E, S48T, V60I, I94L, K122KE, K173AT, Q174K, D177E, T200A, Q207E, R211K, V245Q  
>946| codons 38-247
CEEMEKEGKITKIGPENPYNTPIFAIKKKNSTRWRKLLDFRELNKRTQDFWEVQLGLPHP
AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRTKNPEIVIYQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFITP
DQKHQKEHPFLWMGYELHPDTWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014