<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|SQV NA
2 D4T+DDI+LPV 52
3 3TC+ABC+AZT+LPV 76

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M L10F, Q58E, G73A, L89V I15V, L19I, K20T, M36I, R41K, I62V, L63P, H69K, I85V, I93L  
>354| codons 4-99
TLWQRPFVTIKVGGQITEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFVKVREYDQVP
IEICGKKAIATVLVGPTPANIVGRNVMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69S_SG, M184V, L210W, T215Y D67G K103N A98G T39D, K122E, D123S, I135T, K173V, Q174K, I195V, T200A, Q207E, V245Q N137H, P150PS, S191SA
>354| codons 38-247
CDELEKEGKISKIGPENPYNTPVFAIKKKGSSKWRKLVDFRELNKRTQDFWEVQLGIPHP
GGLKKNKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNHETPGIRYQYNVLSQGWKGSP
AIFQSSMTKILEPFRVKNPDIVIYQYVDDLYVGADLEVGQHRAKIEELREHLWRWGFYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014