<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 IDV|RTI NA
2 D4T+DDI+LPV 52
3 3TC+D4T+EFV+LPV 81
4 3TC+EFV+LPV+TDF 95

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y   K101E, V106M, G190A   T39E, E44D, V60I, W88C, A98S, V118I, K122E, D123N, I135T, K173Q, Q174K, D177E, T200A, E203K, Q207E, K223E, V245Q  
>97| codons 38-247
CEELEKDGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFCEVQLGIPHP
SGLEKKKSMTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRQKNPEIVIYQYVDDLYVASDLEIGQHRAKIKELREHLWRWGFYTP
DKKHQEEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82C, I84V, L90M L10F T12Q, I15V, K20R, M36I, R41K, L63P, H69K, A71V, I93L  
>97| codons 4-99
TLWQRPFVQIKVGGQLREALLDTGADDTVLEEINLPGKWKPKIIGGIGGFVKVRQYDQIP
IEICGKKVIGTVVVGPTPCNVIGRNLMTQLGCTLNF

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014