Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTI | NA |
| 2 | 3TC+AZT+LPV | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, Q61QH, H69K, T74A, L89M, I93L |
| >1175| codons 4-99 TLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDHIL IEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | T39E, S48T, T107S, K122E, D123GS, K173A, Q174QK, D177E, T200A, Q207E, R211RK, V245Q |
| >1175| codons 38-247 CEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVSVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. | PLoS ONE, 2014 |