Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV|RTI | NA |
| 2 | 3TC+D4T+LPV | 52 |
| 3 | 3TC+AZT+LPV | 126 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, K14KR, I15V, M36I, N37D, R41K, D60E, Q61E, H69K, T74TS, L89M, I93L |
| >293| codons 4-99 TLWQRPVVTIRVGGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYEEIL IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215FL | Y181C, G190A | T39E, K64R, T69N, A98S, K101Q, K122E, D123G, A158S, K166R, K173A, Q174QR, D177E, T200A, Q207E, R211K, V245Q |
| >293| codons 38-247 CEEMEKEGKISKIGPENPYNTPVFAIRKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLQKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP SIFQSSMTRILEPFRARNPEIVICQYMDDLYVASDLEIGQHRAKIEELREHLLKWGFLTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. | PLoS ONE, 2014 |