<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NFV|RTI NA
2 3TC+D4T+LPV 52
3 3TC+AZT+LPV 126

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, K14KR, I15V, M36I, N37D, R41K, D60E, Q61E, H69K, T74TS, L89M, I93L  
>293| codons 4-99
TLWQRPVVTIRVGGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYEEIL
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215FL   Y181C, G190A   T39E, K64R, T69N, A98S, K101Q, K122E, D123G, A158S, K166R, K173A, Q174QR, D177E, T200A, Q207E, R211K, V245Q  
>293| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIRKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLQKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTRILEPFRARNPEIVICQYMDDLYVASDLEIGQHRAKIEELREHLLKWGFLTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014