<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NFV|RTI NA
2 3TC+D4T+LPV 52
3 3TC+AZT+LPV 28

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, M36I, N37D, R41K, D60E, Q61E, H69K, L89M, I93L I13K
>293| codons 4-99
TLWQRPVVTKKIGGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYEEIL
IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V T215L     T39E, K64R, T69N, A98S, K122E, D123S, K173A, D177E, T200A, Q207E, R211K, V245Q  
>293| codons 38-247
CEEMEKEGKISKIGPENPYNTPVFAIRKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRAQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFLTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014