<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI NA
2 FTC+LPV+TDF 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, M36I, R41K, I64IM, H69K, K70R, L89M, I93L A28AV
>1745| codons 4-99
TLWQRPLVTIKVGGQLKEALLDTGVDDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL
MEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN       T39E, K43KR, A98S, K122E, D123G, I135R, A158S, K166R, K173T, D177E, T200A, Q207E, R211RK, V245Q I37FL
>1745| codons 37-246
LCEEMEREGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPH
PSGLKKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGS
PSIFQSSMTRILEPFRTQNPEIVIYQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTT
PDKKHQKEPPFLWMGYELHPDKWTVQPIQL

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014