Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 448 | 448 | Israel | 2006 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV|RTI | NA |
| 2 | 3TC+LPV+TDF | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12P, I15V, M36I, R41K, L63Q, H69K, L89M, I93L |
| >448| codons 4-99 TLWQRPLVPIKVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIQ IEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T39E, V60I, K122E, D123S, I135RT, K173T, D177E, T200A, Q207E, D237DN, V245Q |
| >448| codons 38-247 CEEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRTQNPEIVIYQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTP DKKHQKEPPFLWMGYELHPNKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. | PLoS ONE, 2014 |