<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 ABC+DDI+LPV 52

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74IV, M184V, L210W, T215Y K219N   A98G T39E, K43Q, E44D, K122E, D123S, I142V, K173A, Q174K, D177E, T200A, E203K, Q207E, H208Y, R211K, K223E, V245Q P150T
>609| codons 38-247
CEELEQDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGVRYQYNVLTQGWKGSP
AIFQSSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIKELREYLWKWGFYTP
DNKHQEEPPFLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M N83D, L89V L10I, V11L, I13A, K20R, A22V, E35N, M36I, N37D, R41K, I62V, L63P, H69K, A71V, I93L  
>609| codons 4-99
TLWQRPILTAKIGGQLREVLLDTGADDTVLENIDLPGKWKPKIIGGIGGFVKVRQYDQVP
IEICGKKVIGTVLVGPTPADIIGRNVMTQLGCTLNF

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014