<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|SQV NA
2 3TC+D4T+DDI+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, I84V, L90M L10F, L33F, G73A E34EQ, L63P, C67F, H69HQ, A71T, I72L, V77I, I93L  
>31| codons 7-99
QRPFVTIKIGGQLKEALLDTGADDTVFQEMNLPGRWKPKIIGGIGGFVKVRQYDQIPIEI
FGQKTLATVLIGPTPVNVIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, Q151M, T215F K219E G190A   V60I, T69N, K122E, D123E, I135T, V179I, R211K, V245K  
>31| codons 38-247
CTELEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVASDLEIGQHRTKIEELRQHLLKWGFFTP
DEKHQKEPPFLWMGYELHPDKWTVQPIKLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014