Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LV01B | LV01B | Gabon | 2000 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ D4T | 78 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V75T | K70N | V35T, T39N, T69N, K122E, D123S, I135T, S162C, K173S, Q174R, D177E, T200E, Q207A, R211S, V245Q, A272P, K275R, T286A, V292I, I293V, P294T, L295M, I326V, G335D, R356K, M357K, R358K, G359S, T369A, I375V, K390R, A400T, T403M, E404D, E432D |
| >LV01B| codons 1-434 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV FAIKKKDSNNWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRSRNPEIVI YQYMDDLYVGSDLEIGQHREKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGAKALTEIVTMTEEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKKSA HTNDVKQLAEAVQKVATESIVIWGKTPKFRLPIQKETWETWWMDYWQATWIPEWEFVNTP PLVKLWYQLEKDPI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, I15V, E35D, M36I, R41K, K45R, H69K, T74S, L89M |
| >LV01B| codons 1-99 PQITLWQRPVVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Vergne, L | Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries. | JAIDS, 2002 |