<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LV02B LV02B Gabon 2000 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ D4T 30

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35D, M36I, R41K, R57K, K70R  
>LV02B| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGHRAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, V60I, V118I, K122E, T165I, D177E, I178L, T200A, E204K, Q207E, F214L, V245I, D250E, A272P, K275R, Q278E, T286A, E328D, I329V, Y339W, A360T, V381I, K390R, E399D  
>LV02B| codons 1-429
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPELVI
YQYMDDLYVGSDLEIGQHRAKIEKLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIILPEKESWTVNDIQKLVGKLNWASQIYPGIRVKELCKLLRGAKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIADVQKQGQGQWTWQIYQEPFKNLKTGKYARMRGT
HTNDVKQLTEAVQKIATESIIIWGKTPKFRLPIQKETWDAWWTEYWQATWIPEWEFVNTP
PLVKLWYQL

References
Author Title Citation
Vergne, L Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries. JAIDS, 2002