<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LV11L LV11L Gabon 2000 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ D4T 147

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20R, M36I, R41K, H69K, L89M  
>LV11L| codons 1-99
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215Y       V35T, E36D, K49R, V60I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, A272P, Q278H, T286A, E291D, V292I, I293V, P294T, K311R, S322G, I326V, G335D, R356K, M357R, G359T, A371V, I375V, A400T, T403Q, K431Q  
>LV11L| codons 1-433
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDIVTLTEEAE
LELAENREILREPVHGVYYDPGKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRTA
HTNDVKQLTEVVQKVATESIVIWGKTPKFKLPIQKETWETWWQEYWQATWIPEWEFVNTP
PLVKLWYQLEQEP

References
Author Title Citation
Vergne, L Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries. JAIDS, 2002