Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LV11L | LV11L | Gabon | 2000 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ D4T | 147 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20R, M36I, R41K, H69K, L89M |
| >LV11L| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | V35T, E36D, K49R, V60I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, A272P, Q278H, T286A, E291D, V292I, I293V, P294T, K311R, S322G, I326V, G335D, R356K, M357R, G359T, A371V, I375V, A400T, T403Q, K431Q |
| >LV11L| codons 1-433 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDIVTLTEEAE LELAENREILREPVHGVYYDPGKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEVVQKVATESIVIWGKTPKFKLPIQKETWETWWQEYWQATWIPEWEFVNTP PLVKLWYQLEQEP |
References
| Author | Title | Citation |
| Vergne, L | Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries. | JAIDS, 2002 |