<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LV16M LV16M Gabon 2000 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC 91

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, L89M  
>LV16M| codons 1-99
PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       E6D, V35T, T39E, K122E, D123S, I135T, K173A, Q174K, D177E, Q207A, R211N, K238R, V245Q, E248N, D250E, S251D, A272P, A288T, E291D, V292I, I293V, P294V, E312N, G335D, M357K, G359S, K366R, I375V, T377V, K395R, A400T, E432D V8K
>LV16M| codons 1-434
PISPIDTKPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVGSDLEIGQHRTKIEELRAHLLNWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIQLPNKEDWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKTLTDIVVLTEEAE
LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVRQLTEAVQKVAVESIVIWGKTPKFKLPIQRETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPI

References
Author Title Citation
Vergne, L Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries. JAIDS, 2002