<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LV19 LV19 Gabon 2000 HIV1 D Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ D4T 74

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, V35T, E40A, K43E, V60I, V106I, V118I, D121C, K122E, T165I, D177E, I178V, T200E, E204K, F214L, V245T, E248D, D250E, A272P, K281R, R284K, I293V, I329L, G335S, A360T, K366R, A376S, T386I, K390R, E404D  
>LV19| codons 1-434
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTAMEEEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL
CEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPEVVI
YQYMDDLYVGSDLEIGQHREKIEKLRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLKGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGQSQWTYQIYQEPFKNLKTGKYARMRGT
HTNDVRQLTEAVQKISTESIVIWGKIPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I Q18L, L19I, E35D, M36I, P39S, R41K, Q61H, L63P, H69Y, I72V  
>LV19| codons 1-99
PQITLWQRPLVTIKIGGLIKEALLDTGADDTVIEDINLSGKWKPKMIGGIGGFIKVRQYD
HIPIEICGYKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Vergne, L Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries. JAIDS, 2002