Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL263 | IL263 | Israel | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ AZT | 75 |
| 2 | NVP+ 3TC+ AZT | 107 |
| 3 | None | 23 |
| 4 | LPV+ D4T+ DDI | 15 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70KR, M184MV, T215TFIS | F77FL, K219KE | Y181YC | V108VI | T39K, E40D, V60I, K104R, V106I, K166R, K173I, Q174K, D177E, I178ILM, T200A, Q207E, R211K, F214L, L228LR, V245Q |
| >IL263| codons 37-247 ICKDLEKEGKISKIGPENPYNTPIFAIKKKDSTRWRKLVDLRELNKRTQDFWEVQLGIPH PAGLKKKRSITILDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS PAIFQSSMTRILEPFRIKNPEMVICQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLST PDEKHQKEPPFRWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46IL, V82VA | L24I | W6WR, L10LI, I13V, K20I, M36I, R41K, C67E, H69K, L89M | R8RQ |
| >IL263| codons 4-99 TLRQQPIVTVKIGGQLIEALIDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYDQIL IEIEGKKAIGTVLVGPTPANIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |