Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL290 | IL290 | Israel | 1999 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC+ SQV | 83 |
| 2 | AZT+ D4T+ IDV | 95 |
| 3 | D4T+ DDI+ IDV | 42 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82VA, L90LM | V11VI, G73GS | T12TS, I15V, L19LI, K20X, M36I, R41K, K45KR, I62IV, L63X, H69K, A71AV, L89LM, I93L |
| >IL290| codons 4-99 TLWQRPLISIKVGGQIXEALLDTGADDTVLEEINLPGKWKPRMIGGIGGFIKVRQYDQVX IEICGKKVISTVLVGPTPANIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML | T39E, E44ED, S48ST, K122E, D123G, A158AS, K173A, Q174K, D177E, T200A, Q207E, R211RK, T215X, V245Q | N57NK |
| >IL290| codons 37-247 ICEELEKDGKITKIGPENPYKTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPH PAGLKKKKSVTVLDVGDAYFSVPLDEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS PSIFQSSMTKILEPFRAKNPEIVIYQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFXT PDKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |