Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL198 | IL198b | Israel | 2000 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ AZT+ IDV | 22 |
| 2 | D4T+ DDI+ IDV | 29 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T39E, S48T, T58TN, K82KR, K122DE, D123S, E138A, A158AS, S162C, K173E, T200A, Q207A, R211K, V245Q | K223KI |
| >IL198b| codons 37-247 ICEEMEKEGKITKIGPENPYNNPVFAIKKKDSTKWRKLVDFRELNRRTQDFWEVQLGIPH PAGLKKKKSVTVLDVGDAYFSVPLDDSFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGS PSIFQCSMTKILEPFREQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTT PDKKHQIEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, M36I, R41K, H69K, T74A, L89M, I93L |
| >IL198b| codons 4-99 TLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIL IEICGKKAIGAVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |