Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| IL80 | IL80 | Israel | 1999 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 225 |
| 2 | DDI+ AZT | 8 |
| 3 | RTV+ DDI+ AZT | 47 |
| 4 | RTV+ D4T+ DDC | 39 |
| 5 | NFV+ D4T+ DDC | 21 |
| 6 | SQV+ ABC+ 3TC | 7 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | A98G | T39E, S48T, V60I, K122E, D123A, A158S, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q | P119PH, F124I |
| >IL80| codons 37-247 ICEELEKEGKITKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPH PGGLKKKKSVTVLDVGDAYFSVHLDEAIRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS PSIFQSSMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLWKWGFYT PDKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V | K43T | W6WL, T12S, L19I, K20R, E21EG, M36I, R41K, L63P, H69K, A71V, T74A, I93L | G40E |
| >IL80| codons 4-99 TLLQRPLVSIKIGGQIRGALLDTGADDTVLEEINLPEKWTPKMIGGIGGFVKVRQYDQIP IEICGKKVIGAVLVGPTPANVIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Grossman, Z | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |