<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF 26

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, M184I   Y181C V108I, V179E K20R, V35T, E36A, T39K, K43E, S48T, V60I, V90VI, K102Q, K103R, K122E, D123N, Q174K, D177E, V189VI, T200A, R211K, F214L, H221HY, V245Q, A272P, A288S, E291D, V292I, I293V  
>CAS043| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICKEMEEEGKITKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKQRKSVTILDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPEIEI
CQYIDDLYIGSDLEIGQHRAKIEELRQHLLKWGLTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKSLTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E35D, M36I, R41K, K45R, L63P, H69K, L89M, I93L  
>CAS043| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Sunpath, H High rate of K65R for antiretroviral therapy-naive patients with subtype C HIV infection failing a tenofovir-containing first-line regimen. AIDS, 2013