<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC|EFV|D4T NA
2 3TC+EFV+TDF 43

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, K70R, Y115F V75I V106M, Y188C   V35T, T39E, G45E, S48T, V60I, K122E, D123S, K173A, D177E, T200A, Q207E, R211K, V245Q, Y271H, A272S, K277R, T286A, E291D, V292I, I293V, H315Y  
>CAS039| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEEKITKIGPENPYNTPI
FAIKRKDSTRWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAFFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLCVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIHSGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVYGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19T, K20R, M36I, R41K, L63A, H69K, I93L  
>CAS039| codons 1-99
PQITLWQRPLVTIKIGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIAIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Sunpath, H High rate of K65R for antiretroviral therapy-naive patients with subtype C HIV infection failing a tenofovir-containing first-line regimen. AIDS, 2013