Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7907 | CA24813 | U.S. | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 74 |
| 2 | 3TC+D4T+NFV | 186 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10F, N88D | T12P, K14R, I15V, G16E, K20IT, E35G, M36V, R41K, L63T, H69Q, T74S, V77VI, I85IV, L89M, I93L |
| >CA24813| codons 1-98 PQITLWQRPFVPIRVEGQLTEALLDTGADNTVLEGVNLPGKWKPKMIGGIGGFIKVRQYD QITIEICGQKAIGSVLIGPTPVNIVGRDMLTQLGCTLN |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67DN, T69TADN, K70KR, M184V, T215TFIS | K219KQ | V35T, E36ED, T39N, S48T, V60I, D121Y, K122E, I135IT, K173A, D177E, T200A, E203EK, Q207N, R211K, L228LH, V245Q, A272P, K275Q, K277R, E291D, V292I, I293V |
| >CA24812| codons 1-299 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICNELEKEGKITKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIKELRNHLLKWGFSTPDQKHQKEPPFHWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIQVRQLCKLLRGTKALTDIVPLTEEA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |