Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14170 | CA24803 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T | 35 |
| 2 | 3TC+AZT | 13 |
| 3 | 3TC+AZT+NFV | 39 |
| 4 | 3TC+DDI+IDV | 19 |
| 5 | Unknown | 158 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, K14KR, K20MV, R41K, R57K, L63P, I64IV, A71T, I93IL |
| >CA24803| codons 1-99 PQITLWQRPLVTVRIGGQLMEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVKQYD QIPVEICGHKTIGTVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | I135T, I142V, V292I, I293V | L289LR, A299AG, E302E* |
| >CA24802| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKARTEIVPLTEEGE L*L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |