Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MK76 | MK76w52 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | ATV+FTC+RTV+TDF | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19V, E35D, N37NS, R41K, L63T, E65D, H69Y, A71V, I72T, V77I, I93L |
| >MK76w52| codons 1-99 PQITLWQRPLVTIKIGGQVKEALLDTGADDTVLEDMSLPGKWKPKMIGGIGGFIKVRQYD QITIDICGYKVTGTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, R211RK, V245Q, K277KR, T286A, E297A |
| >MK76w52| codons 1-302 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVIPLTAEAE LE |
References
| Author | Title | Citation |
| Mollan, K | HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status. | J Infect Dis, 2012 |