Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MK54 | MK54w50 | U.S. | 2006 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ABC+EFV | 50 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K103N | K20R, E28A, V35T, T39L, V60I, W88C, D121Y, K122E, D123E, I135T, S162N, K173S, Q174K, D177E, T200A, Q207A, R211S, F214L, V245K, E248D, D250E, K281R, T286A, E291D, V292I, I293V |
| >MK54w50| codons 1-301 PISPIETVPVKLKPGMDGPRVKQWPLTAEKIKALTEICLEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL YEEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRSKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTEEAE L |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, M36I, N37S, R41K, L63P, I72V |
| >MK54w50| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Mollan, K | HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status. | J Infect Dis, 2012 |