Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1174 | CA24673 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 4 |
| 2 | DDC | 4 |
| 3 | 3TC+ D4T+ SQV | 165 |
| 4 | 3TC+D4T+SQV | 63 |
| 5 | 3TC+D4T+RTV+SQV | 80 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, V82A, L90M | L10LI, L63P, A71V, V77I, I93L |
| >CA24673| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYD QIPIEICGHKVIGTVLIGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | K43X, R83RK, K122P, I135IV, S162SC, K166KQ, D177E, V179VI, E224ED, A272P, K277R, T286A |
| >CA24672| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEXEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTQILEPFRKQNPEIII YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKDPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |