<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+ABC+EFV 33

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70E V75I G190A, M230L V179D K11R, I50V, R83K, V106I, V118I, D123E, A158S, S163C, T200A, F214L, A272S, K277R, K281R, A288S, I293V, E297K  
>MK239w33| codons 1-299
PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKVGPENPYNTPV
FAIKKKDSTEWRKLIDFRELNKKTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSCMTKILEPFRKQNPDIDI
YQYMDDLYVASDLEIGQHRAKIEELRQHLLRWGLTTPDKKHQKEPPFLWLGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCRLLRGTKSLTEVVPLTKEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, K20R, M36I, N37T, R57K, I64V, C67E  
>MK239w33| codons 1-99
PQITLWQRPLVTIKVGGQLREALLDTGADDTVLEEITLPGRWKPKMIGGIGGFIKVKQYD
QILVEIEGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Mollan, K HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status. J Infect Dis, 2012