Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MK232 | MK232w192 | U.S. | 2009 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | ATV+FTC+RTV+TDF | 192 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| Q58E | I13V, I15IV, E35D, N37E, L63P, I72V |
| >MK232w192| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDMELPGRWKPKMIGGIGGFIKVREYD QIPIEICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| A98S, V118VI, N175H, D177E, V179I, T200E, I202V, E204K, R211K, A272P, K277R, L283I, E297Q |
| >MK232w192| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQHPEIII YQYMDDLYVGSDLEIGQHREKVEKLRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVIPLTQEAE L |
References
| Author | Title | Citation |
| Mollan, K | HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status. | J Infect Dis, 2012 |