Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MK222 | MK222w36 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | ATV+FTC+RTV+TDF | 36 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, M36I, L63T |
| >MK222w36| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QITIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35IL, R83K, K122KE, T139K, S162C, K173KN, T200TA, D250E, A272P, K275R |
| >MK222w36| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRNQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVIPLTEEAE L |
References
| Author | Title | Citation |
| Mollan, K | HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status. | J Infect Dis, 2012 |