Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MK159 | MK159w18 | U.S. | 2006 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ABC+EFV | 18 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V106M | V179D | P4PS, E6EK, K20KR, K103KR, V118I, I142M, Q207E, F214L, V245M, A272P, K277R, T286A, E297EK, K311R |
| >MK159w18| codons 1-328 PISSIKTVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSMTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGMRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIDI YQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVIPLTKEAE LELAENREILREPVHGVYYDPSKDLIAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35ED, R41K, K43R, R57K, D60E, L63P, V77I, V82I, I93L |
| >MK159w18| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMNLPGKWRPKMIGGIGGFIKVKQYE QIPIEICGHKAIGTVLIGPTPINIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Mollan, K | HIV-1 amino acid changes among participants with virologic failure: associations with first-line efavirenz or atazanavir plus ritonavir and disease status. | J Infect Dis, 2012 |