<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V88I, A91T, L101I, K111R, S119K, T124N, T125S, K156N, V165A, K211R, N222H, S230N, I268T  
>hnr19| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEIIPTETGQETAYFILKLAGRWPVRTIHTDNGKN
FTSNSVKAACWWAGIKQEFGIPYNPQSQGVVESMNNELKKIIGQARDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTRELQKQITKIQHFRVYYRDNRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKITRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  I47M K14R, E21K, E35D, L63P, I72V, V77I G40E
>hnr19| codons 1-99
PQITLWQRPLVTIRIGGQLKKALLDTGADDTVLEDMNLPERWKPKMMGGIGGFIKVRQYD
QIPIEICGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R       E40K, D121Y, K122E, I135V, S162C, I195V, T200E, R211G, K219*, K249R, Q278E, I293V, E297K, S322A, Q334L, F346Y, E396K, E399D, T409P, E413K, V417I, V423I, Y427N, E430K, V435G, D443N, E449G, G453E, D460N, R461K, S468T, L491V, K512R E79K, L80P, L283P, G462K
>hnr19| codons 2-560
ISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTKMEKEGKISKIGPENPYNTPVF
AIKRKDSTKWRKLVDFRKPNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLY
EDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEVGQHREKIEELRQHLLGWGFTTPD*KHQKEPPFLWMGYELHPDKWTV
QPIVLPERDSWTVNDIQKLVGKLNWASQIYAGIKVKELCKLPRGTKALTEVVPLTKEAEL
ELAENREILKEPVHGVYYDPAKDLIAEIQKQGLGQWTYQIYQEPYKNLKTGKYARMRGAH
TNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKKTWDAWWTEYWQAPWIPKWEFINTPP
LIKLWNQLKKEPIGGAETFYVNGAANRGTKLEKAGYVTNKKRQKVVTLTDTTNQKTELQA
IHLALQDSGVEVNIVTDSQYALGIIQAQPDRSESELVSQIIEQLIKKEKVYLAWVPAHKG
IGGNEQVDKLVSAGIRKVL

References
Author Title Citation
Li, L Relatively high prevalence of drug resistance among antiretroviral-naive patients from Henan, central China. ARHR, 2013