Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9933 | CA24557 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | 160 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M | V75I, F77L, F116Y | V108VI | K20R, V35I, E79ED, R83K, V118I, E203D, F214L, T286A, A288T, E297K, K311KR, S322T, I329L, A376T, K390R, A400T, A437V, E449D, H483HN, K530R, A554S |
| >CA24557| codons 1-560 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLIDLRDLNKKTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYYSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIDELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKTLTEVIPLTKEAE LELAENREILREPVHGVYYDPTKDLIAELQKQGQGQWTYQIYQEPFKNLKTGKYARMRGA HTNDVKQLTEAVQKITTESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGVETFYVDGAANRDTKLGKAGYVTDRGRQKVVSLTDTTNQKTELQ AINLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKERVYLAWVPAHK GIGGNEQVDKLVSSGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, E35D, N37S, R57K, I62V, L63P |
| >CA24558| codons 1-98 PQITLWQRPLVSIKVGGQLKEALLDTGADDTVLEDMSLPGRWKPKMIGGIGGFIKVKQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLN |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |