Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA4423 | CA24549 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 61 |
| 2 | 3TC+AZT | 17 |
| 3 | 3TC+AZT+IDV | 87 |
| 4 | 3TC+DDI+IDV | 52 |
| 5 | D4T+DDI+EFV+NFV | 17 |
| 6 | D4T+DLV+RTV+SQV | 100 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219Q | K101E, Y181C, G190S | E6D, K20R, K49R, K64R, T69TN, V118I, D123E, I135T, T139K, I178L, T200S, H208Y, R211K, F214L, H221Y, L228LF, V245E |
| >CA24549| codons 1-256 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIRKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DKEFRKYTAFTIPSTNNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI CQYMDDLYVSSDLEIGQHRSKIEELRQYLLKWGLFTPDQKYQKEPPFFWMGYELHPDKWT VQPIELPEKDSWTVND |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I | L24I, F53L, G73T | L10I, I15V, G17E, K20R, E35D, M36I, R41K, K55R, I62V, L63P, A71AT, I72M |
| >CA24550| codons 1-99 PQITLWQRPIVTIKVGEQLREALIDTGADDTVLEDINLPGKWKPKIIGGIGGLIRVRQYD QVPIEICGHKTMTTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |