Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9915 | CA24488 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 23 |
| 2 | 3TC+AZT | 62 |
| 3 | 3TC+D4T+NFV | 55 |
| 4 | None | 22 |
| 5 | 3TC+ABC+AZT | 41 |
| 6 | 3TC+D4T+EFV | 81 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, G16E, N37T, R41K, I62V, L63T, I64L, I72T, V77I |
| >CA24488| codons 1-99 PQITLWQRPLVTIRIEGQLKEALLDTGADDTVLEEMTLPGKWKPKMIGGIGGFIKVRQYD QVTLEICGHKATGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | G190A | V179D | V35T, K103R, I135IL, Q174E, T200A, V245M, A272T, T286A, I293V |
| >CA24487| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKENPDIDI YQYVDDLYVASDLEIGQHRAKIEELRQHLLRWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYTGIKVKQLCKLLRGAKALTEVVPLTEEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |