Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5056 | CA24481 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 117 |
| 2 | 3TC+AZT | 74 |
| 3 | D4T+DDI+NFV | 78 |
| 4 | EFV+RTV+SQV | 92 |
| 5 | None | 37 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69D, L210W | D67G, T215CS | L100I, K103N | T39A, E44D, S68G, K102R, K122E, I142V, V179I, G196E, R211A, D237E, I293V |
| >CA24481| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKDGKISKIGPENPYNTPV FAIKKKGGDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGIKRNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYMDDLYVGSDLEIEQHRTKIEELRQHLWAWGFCTPDKKHQKEPPFLWMGYELHPEKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVVPLTEEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54L, N88NS, L90M | L10LV, R41K, F53Y, Q61H, L63P, K70R, T74TS, V77I, I93IL |
| >CA24482| codons 1-99 PQITLWQRPVVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGYLKVRQYD HIPIEICGHRAIGSVLIGPTPVNIIGRSLMTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |